日批在线视频_内射毛片内射国产夫妻_亚洲三级小视频_在线观看亚洲大片短视频_女性向h片资源在线观看_亚洲最大网

Global EditionASIA 中文雙語Fran?ais
China
Home / China / Innovation

China breaks new ground in medical alpha isotope production

By Li Menghan | chinadaily.com.cn | Updated: 2026-03-30 11:26
Share
Share - WeChat

Alpha isotopes, often described as the "nuclear warhead against cancer", possess high-energy, short-range properties that precisely destroy cancer cells with minimal damage to healthy tissue, offering significant clinical value. However, the separation and purification of alpha isotopes present a significant technical challenge. For years, China's reliance on imports has hindered the development of its next-generation radiopharmaceuticals.

Now, the China Spallation Neutron Source — a major national scientific facility in Dongguan, Guangdong province — has overcome these production challenges by achieving mass production of three key medical alpha isotopes, with an annual output expected to treat over one million patients by 2031.

"Nearly 5 million new cancer cases are diagnosed in China each year, accounting for one-quarter of the global total, with a mortality rate exceeding 50 percent," said Wang Sheng, director of the Spallation Neutron Source Science and professor at the Institute of High Energy Physics of the Chinese Academy of Sciences.

Wang explained that once alpha isotopes enter cancer cells, the radiation they emit can break both strands of the cancer cell's DNA, causing irreversible damage. Additionally, alpha isotopes can induce a "bystander effect" by signaling molecules released from the destroyed cancer cells, which can lead to the death of nearby cancer cells that were not directly exposed to the radiation. This makes them highly valuable for targeted therapy in advanced-stage tumors.

Wang's team has broken free from the long-standing reliance on costly and unstable global supply chains. By utilizing the China Spallation Neutron Source, they harnessed excess beam current from the high-energy linear accelerator to irradiate a stacked thorium target, the raw material for isotope production.

Through a self-developed separation and purification process, scientists were able to extract three key isotopes from the hundreds of isotopic species produced. These are radium-223, actinium-225 and lead-212, which have shown excellent efficacy in treating prostate cancer and neuroendocrine tumors.

Tests confirm a radionuclide purity exceeding 99 percent, with quality comparable to imported ones and marking a successful multipurpose application of the major national scientific facility.

"Compared with traditional nuclear reactors, the China Spallation Neutron Source produces alpha isotopes without relying on neutron irradiation, eliminating the proliferation risks of highly enriched uranium. It also offers flexible production capacity, broader access to raw materials, and significantly lower costs," said Professor Dai Xiongxin who is responsible for the alpha isotope industrialization project.

On Saturday, the Spallation Neutron Source Science Center signed a cooperation agreement with the China Isotope & Radiation Corporation to combine their strengths in research, development, and industrialization to accelerate the transition of China's self-developed alpha radiopharmaceuticals from laboratory research to clinical application.

Dai added that the center is advancing the construction of a dedicated alpha isotope production line to support large-scale clinical applications. Once completed, this facility will have an annual production capacity capable of supplying raw materials for nearly one million patient doses. This expansion is expected to significantly reduce costs, making these treatments more accessible and affordable for patients.

Given the short half-life of these isotopes — which makes long-distance transportation impractical — the project may foster a full-chain industry for targeted alpha therapies in Guangdong in the future, covering from raw material production, drug manufacturing to distribution, Dai added.

Top
BACK TO THE TOP
English
Copyright 1994 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
 
主站蜘蛛池模板: 免费观看黄色一级视频 | 精彩毛片 | 久久中字 | 三级自拍视频 | www.超碰在线观看 | 97色资源 | 国产99精品| 蜜臀99久久精品久久久久久软件 | 亚洲香蕉中文网 | 婷婷亚洲天堂 | 成人国产精品免费观看 | 久久国产视频一区 | www日韩精品 | 久久久精品日韩 | 国产精品一区在线免费观看 | 一区中文字幕 | 成人综合在线观看 | 黄色一极毛片 | 麻豆精品久久 | 日韩首页| 国产精品资源在线 | 久久精品爱 | 亚洲国产视频网站 | 欧美一区二区三区在线看 | 日本黄色免费观看 | 久久精品在线观看视频 | 亚洲伦理影院 | 成人一二三四区 | 久久男人天堂 | 男人影院在线观看 | 深夜视频在线 | 你懂的在线网站 | 久久视频在线观看免费 | 第一福利av| 欧美黄色a级 | 激情久久网站 | 最新国产拍偷乱偷精品 | 中文精品视频 | 国产一级特黄 | 国产精品污视频 | 少妇一级淫片免费播放 |