日批在线视频_内射毛片内射国产夫妻_亚洲三级小视频_在线观看亚洲大片短视频_女性向h片资源在线观看_亚洲最大网

USEUROPEAFRICAASIA 中文雙語Fran?ais
Lifestyle
Home / Lifestyle / Health

Austrian researchers discover potential breakthrough in genetic breast cancer treatment

Xinhua | Updated: 2016-06-01 15:48

Austrian researchers discover potential breakthrough in genetic breast cancer treatment

Researchers at the Austrian Institute of Molecular Biotechnology (IMBA) in Vienna have made a potential breakthrough discovery that could aid in the prevention of genetically-determined breast cancer.[Photo/Xinhua]

Researchers at the Austrian Institute of Molecular Biotechnology (IMBA) in Vienna have made a potential breakthrough discovery that could aid in the prevention of genetically-determined breast cancer.

The team, which conducted the research in collaboration with colleagues from the University of Maryland School of Medicine, found that this form of breast cancer could largely be prevented by blocking a bone gene, the IMBA said in a press release Tuesday.

The institute said this variant of breast cancer is caused by a mutation in the BRCA1 gene, with American actress Angelina Jolie among the more well-known carriers of a "faulty" form of this gene.

Women with this mutation have an up to 87 percent risk of developing breast cancer over their lifetime, Jolie having notably undergone a double mastectomy procedure for this very reason.

The Vienna-based team had in 2010 already shown that sex hormones could trigger breast cancer through proteins called RANKL and their receptor RANK, which are key factors in bone metabolism.

Both are part of the normal process in providing breast cells with signals to tell them to grow. When they become deregulated, breast cells start to divide and multiply and fail to die as they should, ultimately resulting in breast cancer.

The researchers have discovered that blocking the RANKL and RANK system in mice with the mutant BRCA1 gene led to largely normal mammary glands, as opposed to invasive carcinomas found in the control group.

Applying the findings to humans, the researchers noticed that in women who had undergone a preventative mastectomy, RANKL inhibition led to a significant reduction in the growth and spreading of breast tissue cells.

Through the international CIMBA consortium for evaluating the potential genetic modifiers of cancer risk, which maps over 23,000 women, it was also found that genetic variants in the RANK gene are associated with higher risk of the development of cancer in women who carry BRCA1 and also BRCA2 mutations.

Phase III clinical trials are now required to confirm efficacy in humans, the IMBA stated.

 

Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
主站蜘蛛池模板: 天堂岛av| 青青草手机在线视频 | 伊人网在线播放 | 五月综合激情日本mⅴ | 免费视频99 | 亚洲成人影院在线观看 | 98久久| 日韩欧美亚洲综合 | 国产成人精品亚洲男人的天堂 | 亚洲精品一区在线 | 亚洲色图1| 精品国产乱码一区二区 | 国产日韩第一页 | 韩国演艺圈悲惨事件在线 | 亚洲在线免费观看视频 | 国产黄免费| 日韩欧美毛片 | 精品在线免费观看 | 久久草视频在线 | 中文天堂网 | 福利国产 | 成人在线观看一区二区 | 亚欧毛片| 国产精品福利一区 | 成年人网站在线观看视频 | 欧美xxxooo| 免费成人观看 | 国产精品二区一区二区aⅴ污介绍 | 精品国产区一区二 | 一色桃子av| 久久成人毛片 | 久久伊人色 | 日韩一区二区三区在线视频 | 销魂奶水汁系列小说 | 久久久免费观看视频 | 黄色片网站在线播放 | 欧美xxx在线观看 | www日韩精品 | 午夜在线视频观看 | 久久伊人精品 | 午夜男人的天堂 |