日批在线视频_内射毛片内射国产夫妻_亚洲三级小视频_在线观看亚洲大片短视频_女性向h片资源在线观看_亚洲最大网

  Home>News Center>World
         
 

Potential HIV/AIDS vaccine gets more tests
(Agencies)
Updated: 2005-01-25 20:51

NEWARK, N.J. - A potential HIV/AIDS vaccine developed by Merck & Co. that uses synthetic genes to prepare cells to fight the deadly virus is moving into the second stage of testing.

An approved vaccine would be about a decade away if the trial and a third study are successful, said officials with the international coalition that is collaborating on the work.

"It is the most promising candidate that we've seen so far," said Sarah B. Alexander, associate director of the coalition, known as the HIV Vaccine Trials Network, or HVTN. She cautioned, however, "something better could come along tomorrow."

Volunteers began enrolling last month for the Phase II study, which will eventually give the potential vaccine's three doses to 1,500 people in North and South America, the Caribbean and Australia, the network and Whitehouse Station-based drug maker announced Monday.

The study is using male and female volunteers aged 18 to 45 of diverse racial groups who are at high risk for contracting HIV. Participants will receive counseling about how to reduce their risk of HIV infection, Alexander said.

About a dozen companies and organizations worldwide are attempting to develop an AIDS vaccine. Of the 10 associated with HVTN, the Merck candidate is the first to reach Phase II testing, Alexander said.

Of the two that reached Phase III, the final stage before certification is sought, one was deemed unsuccessful in 2000, and another, led by the U.S. Department of Defense, is enrolling volunteers, she said.

The Merck candidate — the MRKAd5 HIV-1 gag/pol/nef, or trivalent, vaccine — is designed to persuade the defenders of each cell, called "killer T cells," to attack HIV when the virus enters the cell. Other vaccines generate an antibody response.

The potential vaccine uses the virus of a common cold, modified so it cannot reproduce or cause people to catch a cold, to transport three synthetically produced HIV genes to the cells.

"We give the body enough of the virus so it can recognize it and create an immune response," but not enough to infect a person, Alexander said.

The Phase I study of the possible vaccine, involving about 1,000 people, "generated strong and durable cellular immune responses against HIV," Merck spokeswoman Janet Skidmore said.

Seattle-based HVTN is funded by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, an agency of the US Department of Health and Human Services, and comprises more than 25 research institutions worldwide.

Merck shares fell 51 cents, or 1.7 percent, to close at $29.85 in Monday trading on the New York Stock Exchange. The stock, which has fallen sharply since Merck withdrew its Vioxx drug from the market amid safety concerns, has traded in a 52-week range of $25.60 to $49.33.



 
  Today's Top News     Top World News
 

China's GDP grows 9.5% in 2004, higher than forecasts

 

   
 

Revision of law to upgrade mine safety

 

   
 

FM says released men to fly back soon

 

   
 

Myanmar nabs drug lord, sends him back

 

   
 

China seeks to curb corruption in big SOEs

 

   
 

Bank officials flee after US$120m go missing

 

   
  Potential HIV/AIDS vaccine gets more tests
   
  Stampede at Hindu procession kills 150
   
  11 policemen killed in Baghdad clashes
   
  UN: World needs the will to stop genocide
   
  Iraq forces arrest top al-Qaida lieutenant
   
  Torture still routine in Iraqi jails: report
   
 
  Go to Another Section  
 
 
  Story Tools  
   
  Related Stories  
   
Shanxi to test blood sellers for HIV
   
Checking mother-to-child HIV transmission
   
India to step up AIDS fight, launch media campaign
   
Boosting rights of HIV victims
   
Thai-Chinese anti-HIV drug 89% effective
   
HIV pregnant women to be treated free
   
HIV infection rates unchanged in US
  News Talk  
  Are the Republicans exploiting the memory of 9/11?  
Advertisement
         
主站蜘蛛池模板: 日韩三级视频 | 欧美日韩三级在线观看 | 亚洲成网 | 丁香婷婷在线 | 91网站免费看 | 国产91精品一区二区 | 久久国产一区二区 | 国产成人精品一区二区三区视频 | 亚洲一区二区三区精品视频 | 蜜挑成熟时在线观看 | 亚洲涩网| 精品久久久久国产 | 中文字幕永久在线视频 | 激情综合五月网 | 欧美xxxxxx片免费播放软件 | 久久在线看 | 中文字幕在线观看视频免费 | 黄色一级视频免费看 | 天天看片中文字幕 | 日韩一级免费视频 | 毛片区| 中文字幕永久在线观看 | 九九爱精品| 97在线免费观看视频 | 日韩在线视频免费播放 | 国产xxxxxx | 免费成人福利视频 | 好男人www社区在线视频夜恋 | 日本成人一区二区 | 日韩欧美一区二区三区在线观看 | 亚洲性欧美 | 奇米影视999| 久久99久久99精品免费看小说 | 亚洲精品一区二区三区在线观看 | 日韩永久免费视频 | 丁香婷婷成人 | 午夜在线播放 | 三级a视频 | 丁香综合五月 | 欧美hdse | 婷婷久草 |