Manny Pacquiao will return to the ring in November, most likely in Macao, and has signed a new two-year contract with promoter Bob Arum that could take him to the end of his career.

Arum said on Tuesday that Juan Manuel Marquez is his first choice for Pacquiao's next fight, but other opponents - including Amir Khan - could be in the mix.

The promoter said a lot depends on whether Oscar De La Hoya emerges victorious in a power struggle within Golden Boy Promotions with his estranged CEO, Richard Schaefer.

"If Oscar takes over the company like he's talking about, we're open to those guys also," Arum said. "The other guy (Schaefer) says he won't deal with me, so we'll see what Oscar says."

Marquez moved into the picture for a fifth fight against Pacquiao with an impressive decision win over Mike Alvarado on May 17.

Marquez, who knocked out Pacquiao the last time they met, is 1-2-1 against the Filipino legend.

Pacquiao, an eight-time world champion, last fought on April 12, beating Timothy Bradley in a rematch of Bradley's controversial decision win in their first fight.

He began his comeback from the Marquez loss last November, when he beat Brandon Rios in the first major fight card at the Venetian Macao's Cotai Arena.

"We're talking to Macao ... that's our first choice," Arum said. "But there are other options. We'll see what Vegas has to offer and there could be an offer from the Middle East. But it will probably be Macao."

Arum, who has promoted Pacquiao since 2005, said the new two-year contract will begin after Pacquiao's next fight and will likely bring him to the end of his career in 2016.

Pacquiao normally fights twice a year, meaning he would have five more fights.

"Manny is the kind of guy who is extraordinarily loyal and he's had a great career with us." Arum said. "We had to work out the different terms and that sort of stuff, but we got it done."

Pacquiao is 35, an age where a lot of fighters begin slowing down, and will be 38 when the latest contract with Arum's Top Rank Promotions expires.

He has been fighting professionally since age 16 and is now 56-5-2 and on the rebound with wins in his past two fights.