Michael Douglas is doing some heavy Brangelina bashing.

"I don't know about Brad Pitt, leaving that beautiful wife to go hold orphans for Angelina," Douglas, referring to ex-Mrs. Pitt Jennifer Aniston, snipes in an interview appearing in the new issue of GQ. "I mean, how long is that going to last?"

Pitt's rep, Cindy Guagenti, and Angelina Jolie's manager, Geyer Kosinski, have not responded to requests for comment by the Associated Press.

CREDIT: STEPHEN LOVEKIN / WIREIMAGE

Douglas, 61, also took aim at Renee Zellweger and Julia Roberts: "I mean, don't ask me what happened with Renee Zellweger. I don't know how you get married for four months. And Julia with Lyle." (Zellweger annulled her four-month marriage to country singer Kenny Chesney last fall, while Roberts divorced singer-songwriter Lyle Lovett in 1995 after a two-year marriage.)

As for his own marriage to Catherine Zeta-Jones, 36, now in its sixth year, Douglas says he's "been fortunate. You learn to respect something of value and nurture it and treat it well."

He was formerly married to Diandra Douglas from 1977-2000.